Curcumin in Turmeric Helps Develop Engineered Blood Vessels and Tissues: Study | Health

According to a new study from the University of California, a compound found in turmeric called curcumin helps develop blood vessels and engineered tissues.

The study results were published in the journal ‘ACS Applied Materials & Interfaces’.

The study indicated that a discovery by UC Riverside bioengineers could accelerate the development of lab-grown blood vessels and other tissues to replace and regenerate damaged tissue in human patients.

Curcumin has anti-inflammatory and antioxidant properties and is known to suppress angiogenesis in malignant tumors.

ALSO READ: World Liver Day 2022: Diet tips, preventive measures to ensure good liver health

Magnetic hydrogels embedded with curcumin-coated nanoparticles promote the secretion of vascular endothelial growth factors.

The possible use of curcumin for vascular regeneration has been suspected for some time but has not been well studied. Huinan Liu, professor of bioengineering at UCR’s Marlan and Rosemary Bourns College of Engineering, led a project to investigate the regenerative properties of curcumin by coating magnetic iron oxide nanoparticles with the compound and mixing them into a biocompatible hydrogel.

UC Riverside bioengineers have now discovered that, when delivered via magnetic hydrogels into stem cell cultures, this versatile compound paradoxically also promotes the secretion of vascular endothelial growth factor, or VEGF, which helps vascular tissues grow.

When cultured with bone marrow-derived stem cells, the magnetic hydrogel gradually released curcumin without damaging the cells.

Compared to hydrogels embedded with naked nanoparticles, the group of hydrogels loaded with curcumin-coated nanoparticles showed a higher amount of VEGF secretion.

“Our study shows that curcumin released from magnetic hydrogels promotes cells to secrete VEGF, which is one of the most critical growth factors for increasing new blood vessel formation,” said co-author Changlu Xu, a doctoral candidate in Liu’s group. which focused on hydrogel research.

The researchers also took advantage of the nanoparticles’ magnetism to see if they could direct the nanoparticles to desired locations in the body.

They placed some of the curcumin-coated nanoparticles in a tube behind pieces of fresh pork tissue and used a magnet to successfully direct the movement of the nanoparticles.

The achievement suggested that the method could eventually be used to deliver curcumin to help heal or regenerate injured tissue.

Liu was joined in the research by her graduate students Radha Daya, Changlu Xu and Nhu-Y. Thi Nguyen at UC Riverside.

Follow more stories at Facebook and Twitter

Please follow and like us:
error20
fb-share-icon
Tweet 20
fb-share-icon20

Sharing is caring!

Related Posts

Nora Fatehi serves up a killer airport look in mint green dress worth ₹32k | Fashion trends

Actress Nora Fatehi knows how to make heads turn with her tailoring choices. The star never shy away from experimenting with her looks and always adds her…

Best and Worst Breakfast Choices for People with Diabetes | Health

Breakfast, arguably the most important meal of the day, serves many purposes, from energizing us for the day ahead, to stimulating the brain, to boosting metabolism. Eating…

Deepika Padukone Wins Airport Fashion Crown With Black And Bralette Look | Fashion trends

Actress Deepika Padukone certainly knows how to make a statement with her fashion choices. Whether she’s walking the red carpet or catching a flight from Mumbai, Deepika…

Desert Nutrition: Expert Tips on What to Drink When You’re Traveling | Health

Summer is that time of year when the skin starts to crack due to dryness, the body becomes dehydrated and the need to moisturize the body over…

Today’s Horoscope: Astrological Forecast for April 20, 2022

Daily Horoscope: Are the stars aligned in your favor? Discover the astrological forecast for Aries, Leo, Virgo, Libra and other zodiac signs for April 20, 2022. Please…

30% of Covid patients develop Covid for a long time: US study finds | Health

About 30% of people infected with COVID-19 developed Long COVID, a set of symptoms that persist for months beyond the initial phase of a SARS-CoV-2 infection, according…

Leave a Reply

Your email address will not be published.

Social media & sharing icons powered by UltimatelySocial